Salmonellae translocated effectors

 

Publications reflecting current work:

1. Vinh D., Ko D., Rachubinsky R, Aitchison J, Miller S.I. Salmonella virulent factor SifA affects Rho Activity on yeast peroxisomes. In revision Molecular Cell Biology. Vinh D et al

2. Levin I, Eakin C, Blanc MP, Klevit RE, Miller SI*, Brzovic PS. Identification of an unconventional E3 binding surface on the UbcH5 ~ Ub conjugate recognized by a pathogenic bacterial E3 ligase. Proc Natl Acad Sci U S A. 2010;107(7):2848-53. PMCID: PMC2840284.* corresponding author Levin et al pnas.0914821107

3. Christen M.*, Coye LH.*, Hontz JS., LaRock D., Pfuetzner R., Megha, Miller SI. Activation of a bacterial virulence protein by the GTPase RhoA. Science Signaling. 2009, 2(95):ra71.  Christen et al

4. Ohlson MB, Huang Z, Alto NM, Blanc MP, Dixon JE, Chai J, et al. Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation. Cell Host Microbe. 2008;4(5):434-46. PMCID: PMC2658612. Ohlson et al.

5. Wasylnka JA, Bakowski MA, Szeto J, Ohlson MB, Trimble WS, Miller SI, and Brumell JH. Role of myosin II in regulating positioning of Salmonella-containing vacuole and intracellular replication. Infection Immunity 2008,(76)6:2722-35. PMCID: PMC2423101. Wasylnka JA et al

6. Haraga A and Miller SI. A Salmonella type III secretion effector interacts with the mammalian serine/threonine protein kinase PKN1. Cellular Microbiology. 2006. 8(5):837-46. Haraga A and Miller SI

7. Haraga A, Ohlson MB, and Miller SI. Salmonellae interplay with host cells. Nature Review Microbiology. 2008. 6(1):53-66. Haraga A, Ohlson MB, and Miller SI