Ingrid Swanson Pultz
Current Research: c-di-GMP signaling in Salmonella Typhimurium. Cyclic diguanylic acid (c-di-GMP) is an important bacterial second messenger that controls a number of important bacterial processes such as motility, exopolysaccharide production, adherence to surfaces, the cell cycle, antibiotic resistance, and virulence. My thesis project involves studying the mechanisms by which c-di-GMP exerts its effects in Salmonella Typhimurium. In addition, I am working on developing new tools to measure the intracellular concentrations of c-di-GMP.
2011 Cell Microbiol – Mills E*, Pultz IS*,, Kulasekara HD, Miller SI. “The bacterial second messenger c-di-GMP: mechanisms of signaling.” Review discussing the diversity of c-di-GMP-metabolizing enzymes and mechanisms of action of this second messenger. *These two authors contributed equally to this work.
2008-2011 Founded the University of Washington International Genetically Engineered Machine (iGEM) team in 2008, and acted as their advisor for the 2008, 2009, 2010, and 2011 teams. The 2010 won Best Health or Medicine Project at the iGEM Jamboree. Visit their wiki here!
2010 PNAS – Costa KC, Wong PM, Wang T, Lie TJ, Dodsworth JA, Swanson I, Burn JA, Hackett M, Leigh JA “Protein complexing in a methanogen suggests electron bifurcation and electron delivery from formate to heterodisulfide reductase.” Work from my second graduate student rotation (in the lab of Dr. John Leigh) published, studying how energy conservation occurs in a model archaea.
2007 Awarded a National Science Foundation Graduate Research Fellowship (NSF GRFP).
2005 As an ARCS Foundation scholar, joined the Department of Microbiology at the University of Washington in the Fall of 2005.
2006 J Virol – Swanson I, Jude BA, Zhang AR, Pucker A, Smith ZE, Golovkina TV “Sequences within the gag gene of mouse mammary tumor virus needed for mammary gland cell transformation.” Although technically employed as a lab tech, I underwent intensive graduate-student-like training in the lab of Tanya Golovkina, studying how the Mouse Mammary Tumor Virus Gag protein effects tumor biogenesis in mice.
University: I always loved molecular biology, and this matured at Wellesley College where I took courses in molecular and cellular biology, biochemistry, organic chemistry, and microbiology courses – and graduated cum laude with a degree in Biology.
Ingrid Swanson Pultz
Miller Lab K-161
Department of Microbiology
1959 NE Pacific St
Seattle, WA 98195