Bridget recently joined Jay Shendure lab, Genome Sciences, University of Washington.

Education:

BS Cell and Molecular Biology, University of Washington.

PhD in Molecular and Cell Biology, 2013.

Publications:

Kulasekara BR, Kamischke C, Kulasekara HD, Christen M, Wiggins PA, Miller SI. c-di-GMP heterogeneity is generated by the chemotaxis machinery to regulate flagellar motilityeLife 2013;2:e01402. PMID: 24347546

Pultz IS, Christen M, Kulasekara HD, Kennard A, Kulasekara B, Miller SI. The response threshold of Salmonella PilZ domain proteins is determined by their binding affinities for c-di-GMP. Mol Microbiol. 2012 Dec;86(6):1424-40. PMID: 23163901

Christen M, Kulasekara HD, Christen B, Kulasekara BR, Hoffman LR, Miller SI. Asymmetrical distribution of the second messenger c-di-GMP upon bacterial cell division. Science. 2010 Jun 4;328(5983):1295-7. PMID: 20522779.

Qiu X, Kulasekara BR, Lory S. Role of Horizontal Gene Transfer in the Evolution of Pseudomonas aeruginosa Virulence. Genome Dyn. 2009;6:126-39. PMID: 19696498.

Kulasekara BR, Jacobs M, Zhou Y, Wu Z, Sims E, Saenphimmachak C, Rohmer L, Ritchie JM, Radey M, McKevitt M, Freeman TL, Hayden H, Haugen E, Gillett W, Fong C, Chang J, Beskhlebnaya V, Waldor MK, Samadpour M, Whittam TS, Kaul R, Brittnacher M, Miller SI. Analysis of the genome of the Escherichia coli O157:H7 2006 spinach-associated outbreak isolate indicates candidate genes that may enhance virulence. Infect Immun. 2009 Sep;77(9):3713-21. PMID: 19564389

Avril M, Kulasekara BR, Gose SO, Rowe C, Dahlbäck M, Duffy PE, Fried M, Salanti A, Misher L, Narum DL, Smith JD. Evidence for globally shared, cross-reacting polymorphic epitopes in the pregnancy-associated malaria vaccine candidate VAR2CSA. Infect Immun. 2008 Apr;76(4):1791-800. PMID: 18250177

Ou HY, He X, Harrison EM, Kulasekara BR, Thani AB, Kadioglu A, Lory S, Hinton JC, Barer MR, Deng Z, Rajakumar K. MobilomeFINDER: web-based tools for in silico and experimental discovery of bacterial genomic islands. Nucleic Acids Res. 2007 Jul;35. PMID: 17537813

Kulasekara BR, Kulasekara HD, Wolfgang MC, Stevens L, Frank DW, Lory S. Acquisition and evolution of the exoU locus in Pseudomonas aeruginosa. J Bacteriol. 2006 Jun;188(11):4037-50. PMID: 16707695

Kulasekara HD, Ventre I, Kulasekara BR, Lazdunski A, Filloux A, Lory S.novel two-component system controls the expression of Pseudomonas aeruginosa fimbrial cup genes. Mol Microbiol. 2005 Jan;55(2):368-80. PMID: 15659157.

Goodman AL, Kulasekara B, Rietsch A, Boyd D, Smith RS, Lory S. A signaling network reciprocally regulates genes associated with acute infection and chronic persistence in Pseudomonas aeruginosa. Dev Cell. 2004 Nov;7(5):745-54. PMID: 15525535.

Wolfgang MC, Kulasekara BR, Liang X, Boyd D, Wu K, Yang Q, Miyada CG, Lory S. Conservation of genome content and virulence determinants among clinical and environmental isolates of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8484-9. PMID: 12815109

Awards:

National Science Foundation Graduate Research Fellowship (NSF GRFP), 2007